Pre-synaptic neuron refers to the nerve cell that sends an electrical impulse to a neighboring neuron. The pre-synaptic neuron sends the impulse by secreting neurotransmitters, which act as chemical signals. These molecules travel from the axon terminal (or end) of the first neuron across the synaptic cleft (the space in between the cells) to the dendrites (or receiving arms) of the second neuron.

See also: Post-Synaptic Neuron

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