Jackson's Law (Jackson's Rule)

Jackson’s law or Jackson’s rule is the principle which states that cognitive decline is caused by neurological conditions and that the higher and recently developed executive functions deteriorate first.

For instance, the brains of patients with Alzheimer’s disease significantly shrink due to the deterioration of brain cells. It first affects the parts responsible for memory and then targets the structures for language and reasoning. Overtime, parts for independent living are affected. This law is attributed to John Hughlings Jackson, an English neurologist.