Hypotonia, also termed as floppy baby syndrome, is typified by having low muscle tone and oftentimes, having reduced muscle strength. It is not a specific medical disease but a symptom of a disorder affecting motor nerves such as Cohen Syndrome, Central Core Disease, and Myotonic dystrophy. Individuals with hypotonia manifest motor skills delay, very flexible joints, weak reflexes, rounded shoulder posture, poor attention, drooling, speech difficulties, and decreased activity tolerance. Infants with hypotonia appear much like rag dolls and often have difficulties in feeding. Also, there is a high risk for neck, jaw, and hip dislocations. Along with pediatric assistance, treatments include physical therapy, speech therapy, and occupational therapy.

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