Belladona alkaloids are nitrogenous organic compounds present in various plants such as Atropa belladona or deadly nightshade, Brugmansia suaveolens or angel’s trumpet, and Hyoscyamus niger or henbane. These alkaloids have toxic anti-cholinergic effects on both central and peripheral nervous systems, causing hallucination, overactive coordinated limb movements, tachycardia, dry mouth, flushed skin, vomiting, and blurry vision. Also, Belladonna delirium is a psychiatric condition characterized by a disturbed mental state which is caused by Belladona alkaloids. On the other hand, such alkaloids are also being used to treat certain medical conditions such as bradycardia (abnormally slow heart rate), tonsillitis, otitis media, and mumps. However, these compounds should be properly regulated as they are proven to be toxic when used in excess. In worst cases, belladonna alkaloids may cause accidental death.