The axon reflex (also known as the flare response) is a peripheral nerve action in which a response from the neurons is sent to organs of the body. So a neuron will send a response directly to an organ. An axon reflex is unique from other neuronal reflexes in that they don't pass through a sensory integration center, such as the spine. So an axon reflex differs from the spinal reflex arc in which efferent neurons carry nerve signals from the spine to the muscles of the body. The axon reflex doesn't involve a centralized location in which the information passes (like the spine). The nerve signals go directly from the neurons to the body.