An Antidepressant is a substance, either natural or man-made, that is used to treat certain mental disorders, among them depression, anxiety, OCD, and many others. These substances are used to influence brain chemistry and the most common classes of these are selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs). Each of these classes of drugs work in different ways to eliminate depressive symptoms. Natural ingredients that are sometimes used for depression treatment are tryptophan and Saint John's Wort.

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